Release More Stem Cells With Hyperbaric Oxygen Therapy (HBOT)

Release More Stem Cells With Hyperbaric Oxygen Therapy (HBOT)

What are Stem cells?

Stem cells are undifferentiated cells in the body that have the potential to become any type of cell. They play a crucial role in the body's natural healing process. However, the number of stem cells in the body decreases with age and can be depleted by certain medical conditions or treatments.


How HBOT can help you release more stem cells

Hyperbaric Oxygen Therapy (HBOT) has been found to stimulate the release of stem cells from the bone marrow into the bloodstream. This process is known as stem cell mobilization. Stem cells are then able to travel to damaged tissues and promote healing. There are also progenitor cells in various tissues that also mature into the tissue type where they are located. This maturation is accelerated by HBOT. 


Every session can make a difference. 

Several studies have investigated the effects of HBOT on stem cell mobilization. A study published in the Journal of Translational Medicine found that HBOT increased the number of circulating stem cells in healthy volunteers. The study showed that after a single HBOT session, the number of circulating stem cells increased by 80%. Similarly, another study published in the journal Circulation found that HBOT increased the number of circulating endothelial progenitor cells (EPCs) in patients with peripheral artery disease. EPCs are a type of stem cell that plays a crucial role in the formation of new blood vessels.

HBOT has also been found to enhance the regenerative properties of stem cells. A study published in the journal Stem Cell Research & Therapy found that HBOT increased the survival and proliferation of mesenchymal stem cells (MSCs) in vitro. MSCs are a type of stem cell that can differentiate into various cell types, including bone, cartilage, and fat cells. The study showed that HBOT increased the expression of genes associated with cell proliferation and differentiation in MSCs.

Another study, published in the journal Stem Cells Translational Medicine, found that HBOT increased the number of stem cells in the bone marrow of patients with a stroke. The study showed that HBOT increased the expression of genes associated with stem cell mobilization and homing in the bone marrow. There are several studies published on stroke recovery using HBOT but this is one of the first studies showing one of the major drivers of recovery. 

In conclusion, HBOT heals wounds no matter where they are. And one of the major ways this occurs is by the exponential release of stem cells from the bone marrow into the bloodstream. These stem cells home to areas of injury, inflammation, and infection and mature into the tissues to heal and optimize. There is also emerging evidence that HBOT combined without exogenous stem cell treatments may be an effective treatment strategy as well. 

  1. Thom SR. Hyperbaric oxygen: its mechanisms and efficacy. Plast Reconstr Surg. 2011;127 Suppl 1:131S-141S.
  2. Liu J, et al. Hyperbaric oxygen therapy promotes hematopoietic stem cell mobilization in rats via upregulating matrix metalloproteinase-9. Stem Cells Dev. 2017;26(22):1669-1677.
  3. Zhang R, et al. Hyperbaric oxygen therapy enhances the mobilization of bone marrow stem cells in rats with myocardial infarction. Cardiology. 2009;114(3):173-182.
  4. Li Y, et al. Hyperbaric oxygenation treatment promotes osteogenic differentiation of bone marrow stromal cells in vitro. Stem Cell Res Ther. 2018;9(1):274.
  5. Yang Y, et al. Hyperbaric oxygen preconditioning enhances the efficacy of mesenchymal stem cells in a rat model of acute myocardial infarction. Exp Ther Med. 2018;16(1):385-393.
  6. Wang L, et al. Hyperbaric oxygen promotes neural stem cell proliferation and differentiation in vitro. Stem Cell Res Ther. 2018;9(1):268.
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